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Refractory Osteomyelitis

Osteomyelitis is an infection of bone. Refractory osteomyelitis is chronic osteomyelitis that has not responded to standard treatment including surgical debridement and antibiotics. Blood flow is often impaired at the site of infection as a result of diabetes, other chronic diseases, and damage from previous surgical procedures. This impaired blow flow decreases the amount of oxygen reaching the site and prevents the body’s normal immune and healing functions from occurring. It also decreases the ability of antibiotics to reach the site of infection.

HBOT works adjunctively with surgical debridement and antibiotics by delivering 100% oxygen to the affected area. Enhanced oxygen levels stimulate the cellular activity of osteoclasts and osteoblasts to build new and healthy bone tissue. HBOT also enhances leukocyte function to better control infection and is thought to enhance the efficacy of systemic antibiotics.

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